Learn how to make homemade Italian pistachio gelato and transport yourself to the streets of Italy with each bite! The main differences between gelato and ice cream is the preparation. Gelato is made in a custard form first, heating it up, and then allowing it to cool down so that the milk proteins bind. This produces the smaller ice crystals and delicate flavor that differentiates it from ice cream. Gelato is definitely one of Italy’s great culinary creations!